Thursday, February 19, 2009

Management of Painful Diabetic Neuropathy

Angus' presentation, which talks about all neuropathy associated with Diabetes Mellitus with a focus on the treatment options available for painful diabetic neuropathy.

Friday, February 13, 2009

Consultant Interview Questions

Helen went for the consultant post in Poole, and has been kind enough to upload a list of the questions that she was asked.

Thursday, February 5, 2009

RD&E Exenatide Audit.

Pam Bowman, the academic F2 has audited the initial use of exenatide at the RD&E.

Exenatide, the first commercially available GLP-1 analogue, has been mentioned in the latest NICE guidelines for those with a BMI >35, an HbA1c >7.5%, on maximum oral metformin and sulphonylurea, who would otherwise be starting a high-cost medication.

NICE also mention criteria for success: a weight loss >5% at one year and improvement in HbA1c >1%

The audit is limited in scope as not many patients have been on the medication 6 months, let alone one year.

The interesting issues are that we are using it off-licence (i.e in those already on insulin) and that doesn't seem to influence outcome.

Here is the audit. Other peoples thoughts, experiences and comments would be useful... just use the comments link at the bottom of this post.


Aspirin for Primary Prevention of Cardiovascular Events in Diabetes: Still an Open Question

This JAMA editorial highlights the uncertainty in the use of aspirin in primary prevention for people with diabetes.

Hopefully the Ascend Trial will help to answer this question.

Below, the Exeter Drugs update (Co-authored by KMM) expands on this issue taking a look at the recently published evidence in the POPADAD and JPAD trials:

Wednesday, February 4, 2009



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